MenoCortex

Decision guide

What are you hoping hormone therapy will help?

A visual map of how clinicians reason about menopausal hormone therapy when brain-related hopes are part of the picture — where the evidence is strong, where it is uncertain, and what belongs in a conversation with the clinician managing your care.

Medically Reviewed

Medically reviewed by Amarish Dave, DO

Board-Certified Neurologist

Last medically reviewed: September 10, 2026

Decision guide · Hormone therapy & the brain

The evidence and the clinical reasoning around menopausal hormone therapy differ enormously depending on what you are hoping it will do. Treating bothersome hot flashes and night sweats is a different question from hoping to protect memory decades from now, and the two get conflated constantly.

So the first question is not whether hormone therapy is good or bad. It is: what are we trying to treat?

This guide will not tell you whether to start, stop, or change hormone therapy, its dose, its formulation or its route. Those decisions need your history, your examination and your priorities, and they belong with the clinician managing your menopause care.

The pathway

  1. Your goal
  2. Symptoms
  3. Age & timing
  4. Medical history
  5. Migraine & aura
  6. Vascular
  7. Route & formulation
  8. Cognition evidence
  9. Dementia evidence
  10. Lifestyle
  11. Discussion

Educational only — not a diagnosis and not medical advice. Your selections stay in this browser tab, are never sent anywhere, and disappear when you close or reload the page. No account, email, name or date of birth is required.